Valerian Root

Scientific Name:
Valeriana officinalis

Common Names:
St. George's Herb, Vandal Root

Active Components:
Valepotriates, GABA, Tyrosine

Common Uses:
Occasional nervousness, nervous tension or anxiety, mild to moderate mood swings or a depressed mood caused by everyday stress, occasional sleeplessness

Available In :
ClarocetNRI, ClarocetERT, ClarocetPM

Clinical References and Resources

 

1. Dietary Supplements and Natural Products as Psychotherapeutic Agents
Adriane Fugh-Berman, MD and Jerry M. Cott, PhD
From the Department of Health Care Sciences (A.F.-B.), George Washington University School of Medicine and Health Sciences, Washington, DC; and Adult Psychopharmacology Program (J.M.C.), National Institute of Mental Health, Rockville, MD.
Psychosomatic Medicine 61:712-728 (1999) [Read the Full Text ]

 

Clinical Trials and Laboratory Tests

 

1. Double blind study of a valerian preparation.
Lindahl O, Lindwall L.
Foellinge Health Center, Sweden.
Pharmacol Biochem Behav. 1989 Apr;32(4):1065-6. PMID: 2678162 [Read the Abstract]

2. The effects of valerian, propranolol, and their combination on activation, performance, and mood of healthy volunteers under social stress conditions.
Kohnen R, Oswald WD.
Psychology Department II, University of Erlangen-Nuremberg, FRG.
Pharmacopsychiatry. 1988 Nov;21(6):447-8. PMID: 3244789 [Read the Abstract]

3. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study.
Andreatini R, Sartori VA, Seabra ML, Leite JR.
Departamento de Farmacologia, Brazil
Phytother Res. 2002 Nov;16(7):650-4. PMID: 12410546 [Read the Abstract]

4. Critical evaluation of the effect of valerian extract on sleep structure and sleep quality.
Donath F, Quispe S, Diefenbach K, Maurer A, Fietze I, Roots I.
Institute of Clinical Pharmacology, Charite University Medical Center, Germany
Pharmacopsychiatry. 2000 Mar;33(2):47-53. PMID: 10761819  [Read the Abstract]

5. Effect of a fixed valerian-Hop extract combination (Ze 91019) on sleep polygraphy in patients with non-organic insomnia: a pilot study.
Fussel A, Wolf A, Brattstrom A.
Zeller AG, Switzerland.
Eur J Med Res. 2000 Sep 18;5(9):385-90. PMID: 11003973 [Read the Abstract]

6. Pharmacodynamic effects of valerian and hops extract combination (Ze 91019) on the quantitative-topographical EEG in healthy volunteers.
Vonderheid-Guth B, Todorova A, Brattstrom A, Dimpfel W.
Pro Science Private Research Clinic GmbH, Germany.
Eur J Med Res. 2000 Apr 19;5(4):139-44. PMID: 10799347 [Read the Abstract]

7. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man.
Leathwood PD, Chauffard F, Heck E, Munoz-Box R.
Pharmacol Biochem Behav. 1982 Jul;17(1):65-71. PMID: 7122669 [Read the Abstract]

8. Comparative study for assessing quality of life of patients with exogenous sleep disorders (temporary sleep onset and sleep interruption disorders) treated with a hops-valarian preparation and a benzodiazepine drug
Schmitz M, Jackel M.
Institut fur Psychosomatik, Austria
Wien Med Wochenschr. 1998;148(13):291-8. PMID: 9757514 [Read the Abstract]

9. Effect of kava and valerian on human physiological and psychological responses to mental stress assessed under laboratory conditions.
Cropley M, Cave Z, Ellis J, Middleton RW.
Department of Psychology, School of Human Sciences, University of Surrey,UK.
Phytother Res. 2002 Feb;16(1):23-7. PMID: 11807960 [Read the Abstract]

10. Stress-induced insomnia treated with kava and valerian: singly and in combination.
Wheatley D.
Psychopharmacology Research Group, UK.
Hum Psychopharmacol. 2001 Jun;16(4):353-356. PMID: 12404572 [Read the Abstract]

11. Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial.
Francis AJ, Dempster RJ.
Department of Psychology and Disability Studies, Royal Melbourne Institute of Technology University,Australia.
Phytomedicine. 2002 May;9(4):273-9. PMID: 12120807 [Read the Abstract]

12. Effect of kava and valerian on human physiological and psychological responses to mental stress assessed under laboratory conditions.
Cropley M, Cave Z, Ellis J, Middleton RW.
Phytother Res 2002;16:23-7. PMID: 11807960 [Read the Abstract]

13. The influence of valerian treatment on "reaction time, alertness and concentration" in volunteers.
Kuhlmann J, Berger W, Podzuweit H, Schmidt U.
Lichtwer Pharma AG, Berlin, Germany.
Pharmacopsychiatry. 1999 Nov;32(6):235-41. PMID: 10599933 [Read the Abstract]

14. Synaptosomal GABA release as influenced by valerian root extract--involvement of the GABA carrier.
Santos MS, Ferreira F, Cunha AP, Carvalho AP, Ribeiro CF, Macedo T.
Department of Zoology, Faculty of Medicine, University of Coimbra, Portugal.
Arch Int Pharmacodyn Ther. 1994 Mar-Apr;327(2):220-31. PMID: 7979830 [Read the Abstract]

15. The scientific basis for the reputed activity of Valerian.
Houghton PJ.
Department of Pharmacy, King's College London.
J Pharm Pharmacol. 1999 May;51(5):505-12. PMID: 10411208 [Read the Abstract]

16. Rational phytotherapy: a physician's guide to herbal medicine.
Schulz V, Hänsel R, Tyler VE.
Berlin: Springer, 1998:81. [View the Book At Amazon]

17. Can valerian improve the sleep of insomniacs after benzodiazepine withdrawal?
Poyares DR, Guilleminault C, Ohayon MM, Tufik S.
Sleep Laboratory of the Department of Psychobiology, Brazil.
Prog Neuropsychopharmacol Biol Psychiatry. 2002 Apr;26(3):539-45. PMID: 11999905 [Read the Abstract]

 

Learn More:

 

Active Ingredients 5-HTP American Ginseng Bacopa German Chamomile Hops Kava Root Lemon Balm Melatonin Passion Flower Rhodiola Rosea St. Johns Wort SAM-e Valerian Winter Cherry   Essential Co-Factors Acetyl-L-Carnitine Choline DMAE GABA Inositol Lecithin Magnesium Rosehips Zinc Vitamin-C Clarocet Essential-b   Learn More Ingredient Reference Library Ingredient Profiles Which Clarocet is right for me? Healthcare Providers

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This website does not provide medical advice. Clarocet products are dietary supplements that are not approved by the FDA to diagnose, treat, cure, or prevent any disease. The health benefits of Clarocet products are supported by independent clinical evaluation. Clarocet products are formulated using a combination of ingredients that are FDA-regulated. Consult with a physician if you believe you are experiencing emotional stress responses such as anxiety, generalized anxiety, social anxiety, panic attacks, depression, mood swings, sleep difficulty or problems focusing and concentrating. Only a qualified healthcare professional can provide you with a correct diagnosis and recommend treatment options.