SAM-e
Scientific name of SAM-e :
S-Adenosylmethionine
Action of SAM-e :
May help to support a healthy neurotransmitter balance; mood enhancer
SAM-e is used for these common wellness concerns:
Mild to moderate mood changes or a depressed mood caused by everyday stress, occasional nervousness, nervous tension or anxiety
Clarocet blends with SAM-e:
Clarocet ERT
The Science and Pharmacology of SAM-e
S-Adenosylmethionine (SAM-e) is a physiological agent that is formed in the liver when the essential amino acid methionine combines with adenosyl-triphosphate (ATP) by way of a process called methylation. It is then broken down and used in over 40 critical biochemical processes throughout the body.
SAM-e has a significant first-pass absorption rate, with approximately 50% of the SAM-e being metabolized in the liver upon oral administration. In laboratory settings, SAM-e has been shown to increase S-Adenosylmethionine levels in cerebrospinal fluid, which indicates that SAM-e is able to pass through the blood-brain barrier. Further laboratory research demonstrates that SAM-e expresses bio activity in the Dopaminergic system. These effects suggest that SAM-e acts as a Natural Reuptake Inhibitor to support a healthy neurotransmitter balance in the brain.
