Lecithin Monograph

Active component of Lecithin:
Choline

Action of Lecithin:
Supports healthy nervous system function; promotes proper utilization of fat-soluble nutrients; promotes normal respiratory function

Find Lecithin in these Clarocet blends:

Clarocet NRI® Immediate Response Capsules™
promote fast-acting relaxation when you need it most.

Clarocet ERT® Extended Release Tablets™
promote positive mood balance all day strong.

Clarocet CS® Controlled Release Tablets™
promote long-lasting energy and mental sharpness.

Clarocet PM® Rapid Release Capsules™
promote a deep, restful night's sleep.

Clarocet Junior® Easy-to-Swallow Tablets™
support Emotional Wellness in kids ages 7 thru 13.

An Overview of Lecithin

Lecithin is a fatty substance most often derived from soybeans. Other sources include foods such as peanuts, eggs and beef products, although significant dietary sources of Lecithin are few.

Choline, which is considered part of the B-Complex vitamins, has been found to be a primary component of Lecithin. In the brain, Choline is a precursor to the neurotransmitter Acetylcholine and is also involved in the synthesis of the neurotransmitter Dopamine. Clinical research shows that taking Choline as a dietary supplement provides positive support for:

  • Healthy nervous system function
  • Healthy cognitive functions such as alertness, concentration and memory
  • Normal respiratory function
  • The utilization of other fat soluble nutrients such as Vitamins E and K

In the United States, Lecithin is classified as GRAS (Generally Recognized as Safe) by the Food and Drug Administration. Substances that receive a GRAS classification have maintained a long, safe history of common use in foods, or have been determined to be safe based on proven scientific research.

Science and Pharmacology of Lecithin

Laboratory analysis has determined that Lecithin consists of the following bioactive components:

  • Choline
  • Inositol
  • Linoleic Acid

Choline, Inositol, Linoleic Acidand other phytochemical constituents derived from Lecithin are cofactors. Cofactors are the most important components required to maintain fundamental processes throughout the body. Basic nervous system functions such as neurotransmitter synthesis and healthy cell-to-cell communication would not be possible without necessary vitamin, mineral and amino acid cofactors.

Supplementing a balanced diet with Lecithin can help to provide positive support for healthy cognitive functions such as alertness, concentration and memory. Because of its nutritive value, Lecithin works best when used along with other essential vitamins, minerals and amino acids that promote emotional wellness and healthy neurological function.

Lecithin Safety and Usage

Lecithin maintains an excellent safety profile. In the United States, Lecithin is classified as GRAS (Generally Recognized as Safe) by the Food and Drug Administration. Substances that receive a GRAS classification have maintained a long, safe history of common use in foods or have been determined to be safe based on proven scientific research. No Recommended Daily Allowance (RDA) exists for Lecithin since it is a nonessential nutrient. In children, a daily dose of five to 50 milligrams is sufficient. Adults are also advised to supplement their diets with Lecithin.

What are the potential side effects of Lecithin?

Side effects are rare and have been documented as mild in clinical study. They may include gastrointestinal discomfort. In the event that you or your child experiences an adverse reaction, discontinue use of this dietary supplement.

Is Lecithin safe for children?

Lecithin is well tolerated when used in children. Because each child is unique, Lecithin should be administered under the supervision of a professional healthcare provider.

Does Lecithin adversely interact with prescription drugs?

Lecithin has no known contraindications. If you or your child is taking a prescription medication, it is recommended that you consult with your prescribing doctor before making any changes or additions to a current treatment plan.

What precautions should I take before beginning Lecithin?

Consult with your healthcare provider before beginning a wellness plan that includes dietary supplements like Lecithin.

Lecithin Clinical Studies

1. Generation of choline for acetylcholine synthesis by phospholipase D isoforms.
Zhao D, Frohman MA, Blusztajn JK.
Department of Pathology, Boston University, School of Medicine, USA.
BMC Neurosci. 2001;2(1):16. Epub 2001 Oct 19. PMID: 11734063 [Read the Abstract]

2. Changes in the interaction between CNS cholinergic and dopaminergic neurons induced by L-alpha-glycerylphosphorylcholine, a cholinomimetic drug.
Trabucchi M, Govoni S, Battaini F.
Farmaco [Sci]. 1986 Apr;41(4):325-34. PMID: 3709792 [Read the Abstract]

3. Cytidine (5')diphosphocholine modulates dopamine K(+)-evoked release in striatum measured by microdialysis.
Agut J, Ortiz JA, Wurtman RJ.
Centro de Investigacion, Grupo Ferrer, Spain
Ann N Y Acad Sci. 2000;920:332-5. PMID: 11193174 [Read the Abstract]

4. The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders.
Comings DE, Comings BG, Muhleman D, Dietz G, Shahbahrami B, Tast D, Knell E, Kocsis P, Baumgarten R, Kovacs BW, et al.
Department of Medical Genetics, City of Hope National Medical Center
JAMA. 1991 Oct 2;266(13):1793-800. PMID: 1832466 [Read the Abstract]

5. Neurobiology of attention-deficit hyperactivity disorder.
Faraone SV, Biederman J.
Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA.
Biol Psychiatry. 1998 Nov 15;44(10):951-8. PMID: 9821559 [Read the Abstract]

6. The dopamine theory of attention deficit hyperactivity disorder (ADHD).
Levy F.
Department of Child and Adolescent Psychiatry, University of New South Wales, Randwick.
Aust N Z J Psychiatry. 1991 Jun;25(2):277-83. PMID: 1652243 [Read the Abstract]

7. The dopaminergic system in attention deficit/hyperactivity disorder.
Ohno M.
Department of Pediatrics, Shiga University of Medical Science, Otsu 520-2192, Japan
genit Anom (Kyoto). 2003 Jun;43(2):114-22. PMID: 12893970 [Read the Abstract]

8. ADHD and Dopmamine - Neurotransmitter.net
Shaw Thomas
Compilation of Clinical Studies [Read the Abstracts]

Related online research destinations

Last Updated: February 2012 [PHMF-02-0]