Bacopa Monograph

Scientific name of Bacopa::
Bacopa monniera

Action of Bacopa:
Support a healthy neurotransmitter balance; promotes positive neurological function

Bacopa is used for these common wellness concerns:
Focus, attention span, concentration, memory, mental sharpness and other healthy cognitive functions; mental and physical fatigue caused by stress

Find Bacopa in these Clarocet blends:

Clarocet NRI® Immediate Response Capsules™
promote fast-acting relaxation when you need it most.

Clarocet ERT® Extended Release Tablets™
promote positive mood balance all day strong.

Clarocet CS® Controlled Release Tablets™
promote long-lasting energy and mental sharpness.

Clarocet PM® Rapid Release Capsules™
promote a deep, restful night's sleep.

Clarocet Junior® Easy-to-Swallow Tablets™
support Emotional Wellness in kids ages 7 thru 13.

An Overview of Bacopa

Bacopa monniera, also know as Water Hyssop, or simply Bacopa, is a prominent remedy in Ayurveda, a holistic system of medicine that originated in India. Historically, the use of Bacopa dates back to the sixth century. Today, practitioners of Ayurveda recognize Bacopa as an adaptogen, a physiological agent that naturally increases the body’s resistance to physical and emotional stress.
Modern research indicates that the active components derived from Bacopa provide positive support for:

  • Focus, attention span, concentration, memory, mental sharpness and other healthy cognitive functions
  • Mental and physical fatigue caused by emotional stress
  • Occasional nervousness, nervous tension and anxiety
  • Healthy immune system function

Bacopa is well tolerated and maintains an excellent safety profile. To date, medical literature confirms that there have been no adverse reactions related to the use of Bacopa as a dietary supplement.

Science and Pharmacology of Bacopa

The majority of contemporary research has focused on the broad spectrum of activity Bacopa demonstrates in the Central Nervous System (CNS). Recent studies indicate that Bacosides, the primary active components of Bacopa, enhance nerve impulse transmission, which may help to promote healthy cognitive functions like focus, concentration, attention span, learning and memory. Preliminary laboratory results also suggest that Bacopa influences the production and availability of the neurotransmitter Serotonin; therefore it is thought that Bacopa may help to provide positive support for healthy neurotransmitter balance.

Bacopa has been identified in clinical analysis as an adaptogen, meaning it increases the body’s resistance to a wide range of chemical, biological and physical stressors. Scientists believe that Bacopa likely affects multiple body systems to promote emotional wellbeing, physical endurance and mental sharpness.

Bacopa Safety and Usage

Bacopa maintains an excellent safety profile when used as directed. In adults and teenagers 14 and older, a dose of 125 to 500 milligrams is recommended to promote healthy cognitive functions such as focus, attention span, concentration, memory and mental sharpness. In children between the ages of seven and 13, a dose of 25 to 100 milligrams is sufficient to support healthy neurological function.

What are the potential side effects of Bacopa?

Side effects are rare and have been documented as mild in clinical studies. They may include gastrointestinal discomfort. In the event that you or your child experiences an adverse reaction, discontinue use of this herb. Bacopa does not cause withdrawal or discontinuation effects.

Is Bacopa safe for children?

Bacopa is generally well tolerated when used by children between the ages of seven and 13. Because each child is different, Bacopa should not be administered without the supervision of a professional healthcare provider.

Does Bacopa adversely interact with prescription drugs?

Taking Bacopa in combination with prescription medications such as benzodiazepines, SSRIs (selective serotonin reuptake inhibitors) or SNRIs (serotonin-norepinephrine reuptake inhibitors) may cause drowsiness. If you or your child is taking a prescription medication, it is recommended that you consult with your prescribing doctor before making any changes or additions to a current treatment plan.

What precautions should I take before beginning Bacopa?

Consult with your healthcare provider before beginning a wellness plan that includes dietary supplements like Bacopa

Bacopa Clinical Studies

1. Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus.
Bhattacharya SK, Bhattacharya A, Kumar A, Ghosal S.
Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi - 221005, India.
Phytother Res. 2000 May;14(3):174-9. PMID: 10815010 [Read the Abstract]

2. Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain.
Chowdhuri DK, Parmar D, Kakkar P, Shukla R, Seth PK, Srimal RC.
Industrial Toxicology Research Center, Lucknow - 226001, UP, India.
Phytother Res. 2002 Nov;16(7):639-45. PMID: 12410544 [Read the Abstract]

3. Adaptogenic effect of Bacopa monniera (Brahmi)
Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK.
Division of Pharmacology, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, India.
Pharmacol Biochem Behav. 2003 Jul;75(4):823-30.PMID: 12957224 [Read the Abstract]

4. A Review of Nutrients and Botanicals in the Integrative Management of Cognitive Dysfunction
Parris M. Kidd, PhD , Biomedical consultant
1999 Thorne Research, Inc.
Volume 4, Number 3,p144-161, 1999 Alternative Review  [Read the Full Text]

5. Clinical evaluation of memory enhancing properties of Memory Plus in children with Attention Deficit Hyperactivity Disorder.
Negi KS, Singh YD, Kushwaha KP, Rastogi CK, Rathi AK, Srivastava JS, Asthana OP, Gupta RC, Lucknow G.
Indian Journal of Psychiatry, 2000 Apr; 42(2) Supplement [Read the Abstract]

6. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects
C. Stough · J. Lloyd · J. Clarke · L. Downey · C. W. Hutchison · T. Rodgers · P. J. Nathan
Neuropharmacology Lab., Brain Sciences Institute, Swinburne U of Technology Australia
Psychopharmacology : 17 April 2001 PMID: 11498727 [Read the Abstract]

7. Chronic effects of Brahmi (Bacopa monnieri) on human memory.
Roodenrys S, Booth D, Bulzomi S, Phipps A, Micallef C, Smoker J.
Department of Psychology, University of Wollongong, Australia.
Neuropsychopharmacology. 2002 Aug;27(2):279-81. PMID: 12093601 [Read the Abstract]

8. Evaluation of sedative and anticonvulsant activities of Unmadnashak Ghrita (Combination Therapy).
Achliya GS, Wadodkar SG, Dorle AK.
Department of Pharmaceutical Sciences, Nagpur University Campus, India.
J Ethnopharmacol. 2004 Sep;94(1):77-83. PMID: 15261966 [Read the Abstract]

9. Studies on the anti-anxiety effect of the medyha rasayana drug, Brahmi
Singh RH, Singh L.
J Res Ayur Siddha 1990;1:133-148.

10. Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats.
Sairam K, Dorababu M, Goel RK, Bhattacharya SK.
Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, India.
Phytomedicine. 2002 Apr;9(3):207-11. PMID: 12046860 [Read the Abstract]

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Last Updated: February 2015 [PHMF-03-0]